hamsters – Communicable Diseases Research

Preclinical efficacy and safety of novel SNAT against SARS-CoV-2 using a hamster model

Article

Published on 2022-12-012022-11-15
Journal: Drug delivery and translational research
[Category] COVID19(2023년), SARS, 치료제,

Pulmonary lesions following inoculation with the SARS-CoV-2 Omicron BA.1 (B.1.1.529) variant in Syrian golden hamsters

시리아 골든 햄스터에서 SARS-CoV-2 Omicron BA.1(B.1.1.529) 변종 접종 후 폐 병변

Article

Published on 2022-12-012022-09-11
Journal: Emerging Microbes & Infections
[Category] COVID19(2023년), SARS, 변종,

Safety and immunogenicity of the first Kazakh inactivated vaccine for COVID-19

Article

Published on 2022-11-302022-11-15
Journal: Human vaccines & immunotherapeutics
[Category] SARS, 진단,

Integrating in silico and in vivo approach for investigating the role of polyherbal oil in prevention and treatment of COVID-19 infection

Article

Published on 2022-11-012022-11-15
Journal: Chemico-biological interactions
[Category] SARS, 변종, 치료제,

[키워드] ACE2 Analysis angiotensin-converting enzyme 2 Anti-inflammatory anti-inflammatory activity antiviral drug approach approved combating Compound contribute Control COVID-19 COVID-19 infection COVID-19 patients cytokine Efficacy ELIXIR entry of SARS-CoV-2 expression FDA GC-MS group groups hamster hamsters human host in silico in vivo in-silico Infection inhibiting inhibitory effect investigated Lung injury male membrane molecular docking molecular docking studies new SARS-CoV-2 PCR Polyherbal oil Prophylactic Protective real time receptor reduced respiratory diseases SARS-CoV-2 selected significantly Spike protein the SARS-CoV-2 Therapeutics Therapeutics. these compound treat Treatment treatment groups Vaccine variants viral envelope Viral load
[DOI] 10.1016/j.cbi.2022.110179 PMC 바로가기

Towards the development of an epitope-focused vaccine for SARS-CoV-2

Article

Published on 2022-10-262022-11-15
Journal: Vaccine
[Category] COVID19(2023년), SARS, 변종, 진단,

Artificial Cell Membrane Polymersome-Based Intranasal Beta Spike Formulation as a Second Generation Covid-19 Vaccine

Article

Published on 2022-10-252022-11-15
Journal: ACS Nano
[Category] COVID19(2023년), SARS, 변종, 비임상, 진단,

[키워드] ACM acute respiratory syndrome adverse effect airway antibodies antibody antigen presenting cells artificial Beta Beta spike C57BL/6 cell membrane clinical symptom clinical trial component conditions coronavirus coronavirus disease COVID-19 CpG cross-neutralizing current delivery of cargo dendritic cells dose doses evaluate evaluated Formulation generate Generation Good hamster hamsters immune responses immunization immunogenic induce Infection initiated interval intranasal mice neutralize neutralizing antibody neutralizing responses New omicron Phase 1 polymersome Practice PROTECT reduction repeated Safety SARS-CoV-2 second serum IgG spike Spike protein Spike-based vaccine Support Toxicity upper respiratory tract Vaccine vaccine. variants viral clearance Viral load virus weight loss wild type
[DOI] 10.1021/acsnano.2c06350 PMC 바로가기

Efficacy of COVID-HIGIV in animal models of SARS-CoV-2 infection

Article

Published on 2022-10-102022-11-15
Journal: Scientific Reports
[Category] COVID19(2023년), SARS, 비임상, 진단,

The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

Article

Published on 2022-10-072022-11-16
Journal: Nature Communications
[Category] COVID19(2023년), SARS, 변종,

Intranasal administration of cold-adapted live-attenuated SARS-CoV-2 candidate vaccine confers protection against SARS-CoV-2

Article

Published on 2022-10-022022-11-15
Journal: Virus research
[Category] COVID19(2023년), SARS, 진단,

SARS-CoV-2 infection impacts carbon metabolism and depends on glutamine for replication in Syrian hamster astrocytes

Article

Published on 2022-10-012022-11-16
Journal: Journal of neurochemistry
[Category] COVID19(2023년), SARS, 치료기술,